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Why girls with breast disease family history must avoid alcohol

Published by Guardian on Thu, 17 Nov 2011


ADDING to research linking alcohol to breast cancer risk, a new study from Washington University School of Medicine in St. Louis, United States shows that adolescent girls with a family history of breast disease ' either cancer or the benign lesions that can become cancer ' have a higher risk of developing benign breast disease as young women than other girls. And unlike girls without a family history, this already-elevated risk rises with increasing alcohol consumption.The Niess-Gain Professor of Surgery and senior author on the study published online November 14 in the journal Cancer, Graham A. Colditz, said: 'The most common question we hear from women with a family history of breast disease is how can we prevent breast cancer in our daughters. This points to a strategy to lower risk ' or avoid increasing risk ' by limiting alcohol intake.'This study is one of the first to look at alcohol consumption in adolescents and the risk of breast disease. Most studies linking alcohol to the risk of developing breast cancer focus on women in their 40s, 50s and 60s and on their risk of invasive breast cancer, not the risk of early, benign lesions that may lead to invasive breast cancer.One such study published November 2 in the Journal of the American Medical Association, in which Colditz was a co-author, found a moderate increase in breast cancer risk with as few as three to six drinks per week for any adult women, regardless of family history.'In the current study, we have tried to disentangle the effects of alcohol in women with a family history that includes both breast cancer and benign breast disease, compared to women with no family history,' Colditz said. 'And we're seeing the strongest effect of alcohol in women with breast disease in the family.
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